Morgan, D. M.*, Horton, B. L.*, Bhandarkar, V.*, Van, R., Dinter, T., Zagorulya, M., Love, J. C., Spranger, S. “Expansion of tumor-reactive CD8+ T cell clonotypes occurs in the spleen in response to immune checkpoint blockade.” Science Immunology, 9, 99 adi3487 (2024). *Equal Contribution
Rodrigues, K. A., Zhang, Y. J., Aung, A., Morgan, D. M., Maiorino, L., Yousefpour, P., Gibson, G., Ozorowski, G., Gregory, J. R., Amlashi, P., Buckley, M., Ward, A. B., Schief, W. R., Love, J. C., Irvine, D. J. “Vaccines combining slow delivery and follicle targeting of antigens increase germinal center B cell clonal diversity and clonal expansion. In Review.
Ma, L., Ramasubramanian, R., Mehta, N. K., Cossette, B., Morgan, D. M., Sukaj, I., Bergaggio, E., Kadauke, S., Meyers, R. M., Paruzzo, L., Ghilardi, G., Grzywa, T. M., Cozzone, A., Schuster, S. J., Frey, N., Zhang, L., Yousefpour, P., Abraham, W., Suh, H., Ruella, M., Grupp, S. A., Chiarle, R., Wittrup, K. W., Irvine, D. J. "Directed evolution-based discovery of ligands for in vivo restimulation of CAR-T cells." In Review.
Lal, M., Burke, C. M., Gautam, R., Mrozek, Z., Trachsel, T., Beers, J., Carroll, M. C., Morgan, D. M., Muir, A. B., Shreffler, W. G., Ruffner, M. A. “Inteferon-γ signaling in eosinophilic esophagitis has implications for epithelial barrier function and programmed cell death.” In Review.
Ma, L., Hostetler, A.*, Morgan, D. M.*, Maiorino, L.*, Sulkaj, I., Yousefpour, P., Whittaker, C. A., Nesser, A., Pires, I. S., Yousefpour, P., Gregory, J., Qureshi, K., Dye, J., Abraham, W., Suh, H., Li, N., Love, J. C., Irvine, D. J. "Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity." Cell, 186, 1-18 (2023). *Equal contribution
Morgan, D. M., Zhang, Y., Kim, J., Murillo, M., Loschko, J., Surendran, N., Patil, S. U., Kanevsky, I., Chorro, L., Love, J. C. “Full-length single-cell BCR sequencing paired with RNA sequencing reveals convergent responses to vaccination”. In Review.
Zagorulya, M., Yim, L., Morgan, D. M., Edwards, A., Torres-Mejia, E., Momin, N., McCreery, C. V., Zamora, I. L., Horton, B. L., Wittrup, K. D., Love, J. C., Spranger, S. "Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer." Immunity 56, 2, 386-405. e10 (2023).
Aung, A., Cui, A., Maiorino, L., Soleimany, A. P., Gregory, J. R., Bukenya, M., Zhang, Y., Lee, H,. Cottrell, C. A., Morgan, D. M., Silva, M., Sug, H., Kirkpatrick, J. D., Amlashi, P., Remba, T., Froehle, L. M., Xiao, S., Abraham, W., Adams, J. A., Love, J. C., Huyett, P., Kwon, D. S., Hacohen, N., Schief, W. R., Bhatia, S. N., Irvine, D. J. "Spatially regulated protease activity in lymph nodes renders B cell follicles a sanctuary for retention of intact antigens." Science, 379, 6630, 332-333, (2023).
Morgan, D. M., Shreffler, W. G., Love, J. C. "Revealing the heterogeneity of CD4+ T cells through single-cell transcriptomics." Journal of Allergy and Clinical Immunology, 150, 748-55 (2022).
Grace, B. E., Backlund, C. M., Morgan, D. M., Kang, B. H., Singh, N. K., Huisman, B. D., Rappazzo, C. G., Mohnihan, K. D., Maiorino, L., Dobson, C. S., Kyung, T., Gordon, K. S., Holec, P. V., Takou Mbah, O. C., Garafola, D., Wu, S., Love, J. C., Wittrup, K. D., Irvine, D. J., Birnbaum, M. E., 'Identification of highly cross-reactive mimotopes for a public T cell response in murine melanoma.' Frontiers in Immunology, 13:886683 (2022).
Miller, T. E., Lareau, C. A., Verga, J. A., DePasquale, E. A. K., Liu, V., Ssozi, D., Sandor, K., Yin, Y., Ludwig, L. S., El Farran, C. A., Morgan, D. M., Satpathy, A. T., Griffin, G. K., Lane, A. A., Love, J. C., Bernstein, B. E., Sankaran, V. G., van Galen, P. "Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations" Nature Biotechnology, 40, 1030-1034. (2022)
Ainciburu, M., Morgan, D. M., DePasquale, E. A. K., Love, J., C., Propser, F., van Galen, P. "WAT3R: Recovery of T-Cell Receptor Variable Regions from 3` Single-Cell RNA Sequencing." Bioinformatisc 8(14):3645-3647 (2022).
Monian, B, Tu, A. A., Ruiter, B., Morgan, D. M., Petrossian, P. M., Smith, N. P., Gierahn, T., M., Ginder, J., Shreffler, W. G., Love, J. C. "Peanut oral immunotherapy differentially suppresses clonally distinct subsets of T helper cells" The Journal of Clinical Investigation. 132(2):e150634 (2022).
Horton, B. L., Morgan, D. M., Momin, N., Zagorulya, M., Torres-Meija, E., Bhandakar, V., Wittrup, K. D., Love, J. C., Spranger, S. (2021). "Lack of CD8+ T cell effector differentiation during priming mediates checkpoint blockade resistance in non–small cell lung cancer." Science Immunology. 6, abi8800 (2021).
Morgan, D. M., Ruiter, B., Smith, N. P., Tu, A. A., Monian, B., Stone, B. E., Virk-Hundal, N., Yuan, Q., Shreffler, W. G., Love, J. C. "Clonally expanded, GPR15-expressing pathogenic effector Th2 cells are associated with eosinophilic esophagitis." Science Immunology, 6, eabi5586 (2021).
Tu, A. A., Gierahn, T. M., Monian, B., Morgan, D. M., Mehta, N. K., Ruiter, B., Shreffler, W. G., Shalek, A. K., Love, J. C. "TCR sequencing paired with massively parallel 3′ RNA-seq reveals clonotypic T cell signatures." Nature Immunology. 20, 1692-1699 (2019).
Oral Presentation and Poster at Gordon Conference on Food Allergy, Ventura, California
Oral Presentation at American Institute of Chemical Engineering Annual Meeting, Boston, MA
Oral Presentation at American Institute of Chemical Engineering Annual Meeting, Oxnard, CA